2026年
2.Songkuan Zhuang#,Weilin Luo#, Beiyi Lan#,Yizhen Liu*.Strategic Design and Engineering of CRISPR/Cas-Powered Sensing Platforms for Enhanced Nucleic Acid Detection.ACS SENSORS. DOI:10.1021/acssensors.6c01710. [link]
1.Songkuan Zhuang#,Ganfeng Deng#,Yuzhong Xu#,Jiajun Han#,Yizhen Liu*.EPILIGHT:precise quantification of single-CpG methylation level with a ratiometric CRISPR strategy.SCIENCE CHINA Chemistry.DOI:https://doi.org/10.1007/s11426-025-3290-x[link]
2025年
7.Yan Zhu#,Junwei Lai#,Xinyao Yang,Shuqing Wang,Dayong Gu,Yan Huang*,Yizhen Liu*,Conghui Liu*.CRISPR/Cas13a-driven lateral flow assay for preamplification-free and ultrasensitive miRNA-21 detection.Biosensors and Bioelectronics.2025,288,117850.[link]
6.Songkuan Zhuang#,Xiaojun Huang#,Muyan Diao#,Ruiling Dong,Yueyu Dong,Jun Liu*,Yizhen Liu*,CONVERT: Dynamic crRNA Reconfiguration for Universal One-Pot CRISPR/Cas12a-Based Nucleic Acid Detection.Analytical Chemistry.2025,97,18776-18785.[link]
5.Songkuan Zhuang#,Botao Bai#,Yizhen Liu*,CRISPR-based SNP detection technologies advance from classical methods to cutting-edge innovations.Chemical communications.2025,61,13345-13358.[link]
4.Songkuan Zhuang#,Yueyu Dong#,Xiaojun Huang,Tonggong Liu,Dayong Gu*,Yizhen Liu*.A universal Cas12a activity regulation strategy via photocleavable crRNA 3’-terminal additives enables one-pot CRISPR detection of arboviruses.Chemical Engineering Journal.2025,521,166699.[link]
3.Siyuan Luo#,Yong Chen#,Zongnan Li#,Xueji Zhang,Yizhen Liu*.Single-tube Lambda exonuclease-mediated LbuCas13a detect of ssDNA for single-nucleotide polymorphisms genotyping.Biosensors and Bioelectronics.2025,288,117760.[link]
2.Jialing Zhong, Yong Chen, Yueyu Dong, Chuanghao Guo, and Yizhen Liu*.SPARC: An Orthogonal Cas12a/Cas13a Dual-Channel CRISPR Platform for Reliable SNV Identification and Mutation Confirmation.Analytical Chemistry.2025,97,27,14629-14636.[link]
1.Xiaolong Wu#, Siyuan Luo#, Chuanghao Guo, Yi Zhao, Jialing Zhong, Ronghuan Hu, Xinyao Yang, Conghui Liu, Qianling Zhang, Songkuan Zhuang, Yong Chen*, Yizhen Liu * , and Xueji Zhang*.LbuCas13a directlytargets DNA and elicits strong trans-cleavage activity. Nature Biomedical Engineering. 2025,9,2141-2154.[link]
2024年
3.Jialing Zhong, Xiaolong Wu, Chuanghao Guo, Conghui Liu, Qianling Zhang, Yong Chen*,and Yizhen Liu*. A Single-Tube, Single-Enzyme Clustered Regularly Interspaced Short Palindromic Repeats System (UNISON) with Internal Controls for Accurate Nucleic Acid Detection.Analytical Chemistry.2024,96,49,19348-19353.[link]
2.Qiang Fu, Jiaheng Li, Stephan Handschuh-Wang, Xuechang Zhou, Yizhen Liu*. Synergistic effect of NiFe2O4 and MWCNTs for ppb-level acetone detection at 150oC. Sensors and Actuators B: Chemical. 2024, 136948, 0925-4005.[link]
1.Ronghuan Hu, Chuanghao Guo, Conghui Liu, Qianling Zhang, Xueji Zhang, Yong Chen*, and Yizhen Liu*. From Lab to Home: Ultrasensitive Rapid Detection of SARS-CoV-2 with a Cascade CRISPR/Cas13a-Cas12a System Based Lateral Flow Assay. Analytical Chemistry. 2024, 96, 35, 14197–14204.[link]
2023年
4.Xiaolong Wu, Yi Zhao, Chuanghao Guo,Conghui Liu, Qianling Zhang, Yong Chen*, Yizhen Liu*, Xueji Zhang. RatioCRISPR: A ratiometric biochip based on CRISPR/Cas12a for automated and multiplexed detection of heteroplasmic SNPs in mitochondrial DNA. Biosensors Bioelectronics. 2023, 241, 115676. [link]
3.Yong Chen, Yibin Zhang, Siyuan Luo, Xinyao Yang, Conghui Liu, Qianling Zhang, Yizhen Liu*, Xueji Zhang. Foldback-crRNA-Enhanced CRISPR/Cas13a System (FCECas13a) Enables Direct Detection of Ultrashort sncRNA. Analytical Chemistry. 2023, 95, 42, 15606-15613. [link]
2.Yibin Zhang#, Yong Chen#, Qianling Zhang, Yizhen Liu*, Xueji Zhang. An aM-level sensitive cascade CRISPR-Dx system (ASCas) for rapid detection of RNA without pre-amplification. Biosensors Bioelectronics. 2023, 230, 115248.[link]
1.Xinyao Yang, Chuanghao Guo, Qianling Zhang, Yong Chen*, Yizhen Liu*, Xueji Zhang. A portable thermostatic molecular diagnosis device based on high-efficiency photothermal conversion material for rapid field detection of SARS-CoV-2. Talanta. 2023, 258, 124422. [link]
2022年
2.Yong Chen, Xiaoling Xu, Jiachun Wang, Yibin Zhang, Wentao Zeng, Yizhen Liu*, and Xueji Zhang. Photoactivatable CRISPR/Cas12a Strategy for One-Pot DETECTR Molecular Diagnosis. Analytical Chemistry. 2022, 94, 27, 9724–9731. [link]
1.Weiyang Tang, Yibin Zhang, Jiachun Wang, Yi Zhao, Xiaoling Xu, Conghui Liu, Yizhen Liu*, and Xueji Zhang. High-Selectivity Single-Nucleotide Variant Capture Technology Based on the DNA Reaction Network. Analytical Chemistry. 2022, 94, 15, 5838–5845. [link]
2021年
4.Qichen Huang, Xuechen Liang, Chongyuan Yan, Yizhen Liu*. Review of interface solar-driven steam generation systems: High-efficiency strategies, applications and challenges. Applied Energy. 2021, 283, 116361. [link]
3.Yun Tan,Xiaohui Zhang, Weiyang Tang, Weiye Zhong, Jin Fan, Donghua Guo, Xiaolong Wu, Yizhen Liu*. Entropy-driven catalytic amplification adjusted by stoichiometry for single-nucleotide variants detection with high abundance sensitivity. Analytica Chimica Acta. 2021,8;1145:3-8. [link]
2.Qichen Huang, Xuechen Liang, Xinjie Zhang, Chongyuan Yan, Jun Liang,Hao Tang, Yizhen Liu*. Efficient-heat-utilization 3D T-shaped porous sponge assists 2D photothermal films to achieve self-acting salt rejection and extra evaporation under high-concentration brine. Desalination. 2021, 499, 114806. [link]
1.Qiuhong Zhang, Junmin Zhang, Jun Song, Yizhen Liu*, Xiangzhong Ren*, Yanli Zhao*. Protein-Based Nanomedicine for Therapeutic Benefits of Cancer. ACS Nano. 2021,25;15(5):8001-8038. [link]
2020年
5.Weiyang Tang#, Weiye Zhong#, Yun Tan#, Guan A. Wang#, Feng Li*, Yizhen Liu*. DNA Strand Displacement Reaction: A Powerful Tool for Discriminating Single Nucleotide Variants. Topics Current Chemistry. 2020, 378, 10.[link]
4. Xuechen Liang, Xinjie Zhang, Zhipeng Liu, Qichen Huang, Han Zhang, Changkun Liu, Yizhen Liu*. Direction-limited water transport and inhibited heat convection loss of gradient-structured hydrogels for highly efficient interfacial evaporation. Solar Energy. 2020, 201, 581-588.[link]
3. Yun Tan, Weiye Zhong, Weiyang Tang, Jin Fan, Xiaohui Zhang, Donghua Guo, Xiaolong Wu, Yizhen Liu*. Improvement of Molecular Diagnosis Using Domain-Level Single-Nucleotide Variants by Eliminating Unexpected Secondary Structures. Chemistry Europe. 2020 , 9;26(69):16256-16260. [link]
2. Xinjie Zhang# , Xuechen Liang# , Qichen Huang, Han Zhang* , Changkun Liu* , Yizhen Liu* . Equipment-free photothermal effect promoted self-healing and self-recovery of hydrogels. Soft Matter. 2020, 21;16(43):9833-9837. [link]
1. Xuechen Liang, Xinjie Zhang, Qichen Huang,Han Zhang, Changkun Liu,Yizhen Liu*, Simple preparation of external-shape and internal-channel size adjustable porous hydrogels by fermentation for efficient solar interfacial evaporation. Solar Energy 2020, 208, 778-786.[link]
2019年
3. Weiyang Tang, Weiye Zhong, Jin Fan, Yun Tan, Qichen Huang and Yizhen Liu*, Addressable activated cascade DNA sequential logic circuit model for processing identical input molecules, Chem. Commun., 2019, Advance Article. [link]
2. Weiye Zhong, Weiyang Tang, Yun Tan, Jin Fan, Qichen Huang, Danli Zhou, Weimin Hong and Yizhen Liu*. A DNA arithmetic logic unit for implementing data backtracking operations. Chem. Commun., 2019,55, 842-845. [link]
1. Yizhen Liu*, Zhipeng Liu, Qichen Huang, Xuechen Liang, Xuechang Zhou*, Huide Fu,a Qixing Wu, Junmin Zhang and Wei Xie*, A high-absorption and self-driven salt-resistant black gold nanoparticle-deposited sponge for highly efficient, salt-free, and long-term durable solar desalination. Journal of Materials Chemistry A. 2019, 7, 2581-2588. [link]
2018年
1. W. Y. Zhong, W. Y. Tang, J. Fan, J. M. Zhang, X. C. Zhou and Y.Z. Liu*, A Domain Based DNA Circuit for Smart Single-Nucleotide Variants Identification, Chem. Commun., 2018,54, 1311-1314.（Back Cover） [Link]
2017年
11. Xin-Yi Li, Fu-Yan Feng, Zi-Tong Wu, Yi-Zhen Liu, Xiao-Dong Zhou* and Ji-Ming Hu*, High stability of gold nanoparticles towards DNA modification and efficient hybridization via a surfactant-free peptide route, Chem. Commun., 2017,53, 11909-11912. [link]
10. T. Zhang, W. W. Liang, Y. X. Huang, X. R. Li, Y.Z. Liu, B. Yang, C. X. He, X. C. Zhou, J. M. Zhang*,Biofunctional organic sponge photocatalyst for efficient cross-dehydrogenative coupling of tertiary amines to ketones, Chem. Commun., 2017,53, 12536-12539. [link]
9. Z. Liu, Z. Yang, X. Huang, C. Xuan, J. Xie, H. Fu, Q. Wu, J. Zhang, X. Zhou and Y. Liu*, High-absorption recyclable photothermal membranes equipped in bionic system for high-efficiency solar desalination via enhanced localized heating, Journal of Materials Chemistry A, 2017,5, 20044-20052 .[link]
8. T. Z#. Li, J#. H. Wang, J. B. Yang, M. Y. Yang, D. Y. Zhu, X. H. Zhou, S. Handschuh-Wang, Y. Z. Liu*, X. C. Zhou, “Freezing”, Morphing, and Folding of Stretchy Tough Hydrogels, Journal of Materials Chemistry B, 2017, 5, 5726-5732. [link]
7. J. B. Yang#, T. J. Zhou#, L. Y. Zhang, D. Y. Zhu, S. Handschuh-Wang, Z. Liu, T. T. Kong, Y. Z. Liu*, J. M. Zhang,X. C. Zhou*, Defect-Free, High Resolution Patterning of Liquid Metals by Reversibly Sealed, Reusable Polydimethylsiloxane Microchannels for Flexible Electronic Applications, Journal of Materials Chemistry C, 2017, 5, 6790-6797. [link]
6. T. J. Zhou, J. B. Yang, D. Y.Zhu, J. Y. Zheng, S. Handschuh-Wang,X. H. Zhou,J. M. Zhang, Y. Z. Liu*, C. X. He,X. C. Zhou, Hydrophilic Sponges for Leaf-Inspired Continuous Pumping of Liquid, Advanced Science, 2017, 4, 1700028. [link]
5. Y. Z. Chen#, Z. Liu#, D. Y. Zhu, S. Handschuh-Wang, S. Q. Liang, J. B. Yang, T. T. Kong, X. H. Zhou, Y. Z. Liu, X. C. Zhou*, Liquid Metal Droplets with High Elasticity, Mobility and Mechanical Robustness, Materials Horizons., 2017,4, 591-597. [link]
4. Y. Y. Li, D. Y. Zhu, S. Handschuh-Wang, G. H. Lv, J. H. Wang, T. Z. Li, C. C. Chen, C. X. He, J. M. Zhang, Y. Z. Liu*, B. Yang,X. C. Zhou*, Bio-Inspired, Mechano-Regulated Interfaces for Rationally Designed, Dynamically Controlled Collection of Oil Spills from Water, Global Challenges,2017,1,1600014. [link]
3. Liang Suqing, Li Yaoyao, Chen Yuzhen, Yang Jinbing, Zhu Taipeng, Zhu Deyong, He Chuanxin, Liu Yizhen*, S. Handschub-wang, Xuechang Zhou*,Liquid Metal Sponges for Mechanically-Durable, All-Soft, Electrical Conductors, Journal of Materials Chemistry C, 2017, 5, 1586-1590. [Back Cover] [link]
2. Weiyang Tang#, Qichen Huang#, Zhenjie Yang#, Qiwei Zheng, Lihong Wang, Junmin Zhang, Liang Chen, Xuechang Zhou, Yizhen Liu* and Jiming Hu, A DNA Kinetics Competition Strategy of Hybridization Chain Reaction for Molecular Information Processing Circuits Construction, Chemical Communications, 2017, 53, 1789-1792. [Outside Front Cover] [link],(深圳大学首篇本科生第一作者的一区论文)
1. Suqing Liang,Yaoyao Li, Tingjiao Zhou,Jinbin Yang,Xiaohu Zhou,Taipeng Zhu,Junqiao Huang,Julie Zhu, Deyong Zhu,Yizhen Liu,Chuanxin He,Junmin Zhang and Xuechang Zhou*, Mirofluidic Patterning of Metal Structures for Flexible Conductors by in situ Polymer-Assisted Electroless Deposition, Advanced Science, 2017, 4, 1600313. [Link]
2016年
Liang Suqing, Li Yaoyao, Yang jinbing, Zhang Junmin, He Chuanxin, Liu Yizhen*, Zhou Xuechang*, 3D stretchable, Compressible, and Highly Conductive Metal-coated Polydimethylsiloxane Sponges, Advanced Materials Technologies, 2016, 1, 1600117. [Frontispiece(卷首页亮点论文)] [Link]
2015年
2. Wu Zitong, Yifei Liu, Yizhen Liu, Huaming Xiao, Aiguo Shen, Xiaodong Zhou*,Jiming Hu*.A Simple and Universal “Turn-on” Detection Platform for Proteases Based on Surface Enhanced Raman Scattering (SERS). Biosensors and Bioelectronics,65, (2015): 375-381. (IF=7.476) [link]
1. Liu Yizhen, Wu Zitong, Zhou Xiaodong, Hu jiming*.Research Progress of DNA Optical Logic Gate. Acta Laser Biology Sinica, 2015, 24, 1, 8-16.[link]
2012-2014年
7. Mao Kang, Yizhen Liu, Huaming Xiao, Yinran Chen, Zitong Wu, Xiaodong Zhou*, Aiguo Shen, Jiming Hu. A Novel Platform for Detection of Protooncogene Based on Au Nanoclusters Enhanced Fluorescence. Analytical Methods,2015,7, 40-44. (IF=1.915) [link]
6. Yizhen Liu, Wei Fang, Zitong Wu, Guohua Zhou, Wen Yi, Xiaodong Zhou, Aiguo Shen，Jiming Hu*. A One-Tube Multiplexed Colorimetric Strategy Based on Plasmonic Nanoparticles Combined with Non-Negative Matrix Factorization. Talanta，128, (2014): 305-310. (IF=4.035) [link]
5. Yizhen Liu, Boran Dong, Zitong Wu, Wei Fang, Guohua Zhou, Aiguo Shen, Xiaodong Zhou*, Jiming Hu*. Toehold-Mediated DNA Logic Gates Based on Host-Guest DNA-GNPs. Chemical Communications,2014,50, 12026-12029. [Back Cover] (IF=6.567) [link]
4. Zhou Guohua, Yizhen Liu, Ming Luo, Xiuhong Li, Qinfeng Xu, Xinghu Ji, Zhike He*. Controlled Assembly of Gold Nanoparticles through Antibody Recognition: Study and Utilizing the Effect of Particle Size on Interparticle Distance. Langmuir,29, 15 (2013): 4697-4702. (IF=3.993) [link]
3. Wu Zitong, Yizhen Liu, Xiaodong Zhou, Aiguo Shen*, Jiming Hu*. A “Turn-Off” SERS-Based Detection Platform for Ultrasensitive Detection of Thrombin Based on, Enzymatic Assays. Biosensors & Bioelectronics,44,(2013): 10-15. (IF=7.476) [link]
2. Yizhen Liu#, Zitong Wu#, Guohua Zhou, Zhike He, Xiaodong Zhou, Aiguo Shen, Jiming Hu*. Simple, Rapid, Homogeneous Oligonucleotides Colorimetric Detection Based on Non-Aggregated Gold Nanoparticles. Chemical Communications，48, 26 (2012): 3164-3166. (IF=6.567) [link]
1. Guohua Zhou, Yizhen Liu, Ming Luo, Qinfeng Xu, Xinghu Ji, and Zhike He*, Peptide-Capped Gold Nanoparticle for Colorimetric Immunoassay of Conjugated Abscisic Acid. ACS Applied Materials & Interfaces, 2012,4,9,5010-5015. (IF=7.145) [link]
国际或全国学术会议论文
7.郑祺玮，钟玮晔，王力弘，刘翼振，SERS检测技术在DNA逻辑电路中的应用，首届全国生物医学拉曼光谱学术会议，武汉，2016.11.4-11.6。
6.王力弘，郑祺玮，刘翼振，基于DNA逻辑门的智能分子诊断技术，中国化学会第30届学术年会，大连，2016.07.04-07。
5. Yizhen Liu, Boran Dong, Zitong Wu, Wei Fang, Aiguo Shen, Xiaodong Zhou, Jiming Hu*, SERS readout for tunable toehold-mediated DNA logic gates. The 24th International Conference on Raman Spectroscopy，Jena，2014.8.10-15。
4.刘翼振，方威，伍子同，周国华，易雯，周晓东，沈爱国，胡继明*，SPR活性纳米粒子构建的比色法传感器同时检测两种DNA，第十七届全国光散射学术会议摘要文集，266页，西安，2013.10.19。
3. Yizhen Liu, Zitong Wu, Aiguo Shen，Jiming Hu*，toehold displacement for DNA SERS detection using Au@Ag core-shell nanoparticles，The 23rd International Conference on Raman Spectroscopy, Bangalore, 2012.8.12-17。
2.刘翼振，伍子同，周晓东，沈爱国，胡继明*, 非聚集态纳米金与磁珠联用比色检测寡聚核甘酸序列,第十一届全国分析化学年会，青岛，2012.10.26-29。
1.刘翼振，伍子同，沈爱国，胡继明*，表面增强拉曼光谱同时检测双组分寡聚核苷酸，第十六届全国光散射学术会议论文摘要集，121-121页，厦门，2011.11.25。
1.Weiyang Tang, Yibin Zhang, Jiachun Wang, Yi Zhao, Xiaoling Xu, Conghui Liu, Yizhen Liu*, and Xueji Zhang.High-Selectivity Single-Nucleotide Variant Capture Technology Based on the DNA Reaction Network.Anal. Chem. 2022